RESEARCH

This FOA encouarges multidisciplinary and interdisciplinary research to elucidate how Apolipoprotein E, lipoprotein receptors and CNS lipid homeostasis influence brain aging and the transition to neurodegeneration in Alzheimers disease (AD). The ultimate goal is to gain an in depth understanding of the mechanisms by which the Apolipoprotein E e4 allele confers increased AD risk for the purpose of advancing the overall search for efficacious AD treatments and Apolipoprotein E e4-directed therapeutics in particular. Grant details at: http://www07.grants.gov/search/search.do?&mode=VIEW&flag2006=false&oppId=48322

This Funding Opportunity Announcement (FOA) issued by the National Institute on Deafness and Other Communication Disorders (NIDCD), National Institutes of Health (NIH) encourages R01 applications that focus on Proteomics in Auditory Developmental and Disease Processes. Grant details at: http://www07.grants.gov/search/search.do?&mode=VIEW&flag2006=false&oppId=48332

The Enduring Questions grant program supports a faculty member’s development of a new course that will foster intellectual community through the study of an enduring question. This course will encourage undergraduate students and a teacher to grapple with a fundamental question addressed by the humanities, and to join together in a deep and sustained program of reading in order to encounter influential thinkers over the centuries and into the present day. Grant details at: http://www.neh.gov/grants/guidelines/EnduringQuestions.html

The Office of Research on Women’s Health (ORWH), participating Institutes and Centers (ICs) of the National Institutes of Health (NIH), and the Office of Dietary Supplements (ODS) announce a continuing program for administrative supplements to research grants to support individuals with high potential to re-enter an active research career after taking time off to care for children or attend to other family responsibilities. The aim of these supplements is to encourage such individuals to re-enter research careers within the missions of all the program areas of NIH. This program will provide administrative supplements to existing NIH research grants for the purpose of supporting full-time or part-time research by these individuals in a program geared to bring their existing research skills and knowledge up to date. It is anticipated that at the completion of the supplement, the re-entry scientist will be in a position to apply for a career development (K) award, a research award (R), or some other form of independent research support. Additional details at: http://grants.nih.gov/grants/guide/pa-files/PA-08-191.html

The United Mitochondrial Disease Foundation (UMDF) is committed to finding cures for mitochondrial illness and knows research is the path to success. Yet they also realize that new, aggressive research for rare disorders is often not underwritten by federal grants. UMDF seeks to fund such grants and others which will forward the cause of research into mitochondrial diseases. Consideration is given to all proposals except applications that are continuations of past or current UMDF grants.

Preferential emphasis will be given to proposals relevant to the UMDF’s mission. Both basic science and clincial research proposals will be considered. Proposals fitting one of the following criteria may be given preference:

1. Post-doctoral fellowships
2. Seed money for new researchers
3. New area of research for experienced investigators

This FOA encourages multidisciplinary and interdisciplinary research to elucidate the mechanistic links between psychosocial stress and health in aging, as well as how the aging process and age-related diseases affect the responses to psychosocial stressors. Generally, research should be focused on (1) aging and how neural mechanisms respond to psychosocial stress and affect other body systems, (2) characterizing the behavioral, psychological and social mechanisms and pathways involved in transducing psychosocial stressors into health outcomes, (3) how stressors modulate physiological process underlying life-span, immune mechanisms, and metabolism, and (4) how psychosocial stress contributes to the development or progression of geriatric syndromes, chronic medical conditions, and disabilities in later life. Grant details at: http://grants.nih.gov/grants/guide/pa-files/PA-09-216.html

AHRQ invites applications to develop a prospective clinical registry of orthopedic devices, drugs, and procedures through a practice-based research collaborative and clinical and outcomes data resource (P50 grant mechanism). The goal of this registry initiative is to support the development of a sustainable data infrastructure and to conduct rigorous clinical and scientific research including comparative effectiveness and safety research. Grant details at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HS-10-008.html

The National Aeronautics and Space Administration (NASA) Goddard Space Flight Center’s Learning Technologies Project Office (LTPO) has released a Cooperative Agreement Notice (CAN) to conduct research and evaluation on the design and usage of Massively Multiplayer Online Games (MMOG) and Persistent Immersive Synthetic Environments (Virtual Worlds) for NASA Science, Technology, Engineering and Mathematics (STEM) Education and Training. This solicitation seeks proposals that communicate the required approach and skills to contribute to NASA and other federal agencies, private industry and academia’s research initiatives to improve STEM content and delivery approaches that promote the development of our nation’s future workforce, workforce applications, and missions. The anticipated maximum number of awards is three (3) with an approximate total of $1,650,000 will be available to award as a cooperative agreements under this solicitation. One award of up to $350,000 annually will be made for up to three years to partner with LTPO and the MMOG developer to infuse educational content and design into the NASA MMOG. One award of up to $100K annually is planned to award an independent evaluation effort for up to three years and one award up to $100K annually is planned to conduct broad-based research of the applicability of educational gaming to diverse institutions and people. The LTPO NASA Cooperative Agreement Notice is available on the NASA Headquarters solicitations website: http://nspires.nasaprs.com. Additionally, any Frequently Asked Questions (FAQ) that arise after the announcement is released will be posted on NSPIRES.

The FY09 MSRP is pleased to announce the release of two award mechanisms, the Metric Development and Validation and Synergistic Idea Awards. The Program Announcements/Funding Opportunities, including the intent of each award mechanism, eligibility, and submission deadlines; and Application Instructions and General Information is available electronically for downloading from the Grants.gov website (), the CDMRP website () and the CDMRP eReceipt Website(https://cdmrp.org). ---------------------------------------------------------------------- Submission Deadlines: Metric Development and Validation Award Funding Opportunity Number: W81XWH-09-MSRP-MDVA Pre-Application (Pre-proposal): August 13, 2009 Application: November 24, 2009 (Applications will not be accepted unless the PI has received a letter of invitation.) Synergistic Idea Award Funding Opportunity Number: W81XWH-09-MSRP-SIA Pre-Application (Pre-proposal): August 13, 2009 Application: November 24, 2009 (Applications will not be accepted unless the PI has received a letter of invitation.)

AACR Funding Opportunities for Glioblastoma Multiforme (GBM) Research Application Deadline: August 10, 2009 Decision Date: September 14, 2009 Grant Term Begins: On or Around December 1, 2009 Application submission: Online via proposalCENTRAL The AACR-National Brain Tumor Society Fellowship, in memory of Bonnie Brooks, is open to Postdoctoral Fellows and Clinical Research Fellows at an academic facility, teaching hospital, or research institution. Applicants must hold the title of Postdoctoral Fellow or Clinical Research Fellow at an academic facility, teaching hospital, or research institution within the United States. This is a one-year fellowship of $40,000 to support the salary and benefits of Fellows. Inquiries may be directed to Hanna Hopfinger at grants@aacr.org. AACR Funding Opportunities for Anti-Angiogenesis Research Application Deadline: August 10, 2009 Decision Date: September 14, 2009 Grant Term Begins: On or Around December 1, 2009 Application submission: Online via proposalCENTRAL The AACR Judah Folkman Career Development Award for Anti-Angiogenesis Research will be awarded to support research projects restricted to basic, clinical, translational or epidemiological projects that will substantially advance the field of anti-angiogenesis research in cancer. This award is open to junior faculty who completed postdoctoral studies or clinical fellowships no more than three years prior to the start of the grant term; who are in their first full?time, faculty appointment and hold the title of Instructor, Research Assistant Professor, Assistant Professor, or an equivalent full?time faculty appointment; and who are at an academic, medical, or research institution. These are two-year grants of up to $100,000. Up to one grant will be awarded. Inquiries may be directed to Elizabeth Martin at grants@aacr.org

The University's updated F&A rate agreement has been approved for FY10 federal fringe at the rate of 22.5%. See the revised link at "Case Info" at http://ora.ra.cwru.edu/ospa/Caseinfo_2-16-09.doc

Issued on: July 8, 2009
High Interest in ARPA-E’s Initial Funding Opportunity for Transformational Energy Technology
ARPA-E Begins Review of 3,500 Potentially Transformational R&D Proposals

Washington, DC – The Advanced Research Projects Agency – Energy (ARPA-E) of the U.S. Department of Energy (DOE) completed the submission stage of its first Funding Opportunity Announcement (FOA) released April 27th, 2009. ARPA-E has received approximately 3,500 concept papers for the $150 million available as part of this FOA (DE-FOA-0000065).
The large number of submissions – “Concept Papers” - for ARPA-E’s initial FOA outstripped the expectations of industry observers and highlights America’s capacity for Energy technology innovation that can be applied to transformational research and development (R&D).

ARPA-E’s first solicitation is funded through the American Recovery and Reinvestment Act of 2009. The announcement is primarily aimed at prospective applicants who already have a relatively well-formed R&D plan for a transformational concept or new technology that can make a significant contribution if and when successfully deployed. Submitters of the most meritorious Concept Papers will be encouraged to submit Full Proposals. ARPA-E expects to provide responses to Concept Paper applicants by the end of the last week in July on whether a Concept is likely to form a basis of a successful Full Proposal. The deadline for Full Proposals is expected to be the end of August.
ARPA-E is currently planning future solicitations as part of its ongoing mission to fund and support transformational energy-related technology research and development. For more information about ARPA-E, including updated FAQs, please visit http://arpa-e.energy.gov/