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Copyright 2007 Crain Communications
All Rights Reserved
Crain's Cleveland Business

April 9, 2007

SECTION: COVER STORY; Pg. 1

LENGTH: 1054 Wörter

HEADLINE: NIH ups grants given to area institutions;
Case, Clinic and others submitting more proposals to offset fed agency's flat budget

BYLINE: SHANNON MORTLAND

BODY:


As other universities and academic medical centers grapple with cuts in research dollars coming from the National Institutes of Health, Cleveland institutions are bucking the trend.

Case Western Reserve University, the Cleveland Clinic, MetroHealth Medical Center, University Hospitals Case Medical Center and the Louis Stokes Cleveland Veterans Affairs Medical Center all have increased the amount in NIH research grants they have received in recent years.

``Even though there have been tough times ... we seem to be doing quite well,'' said Paul DiCorleto, chairman of the Clinic's Lerner Research Institute.

In the last three years, the NIH budget has remained relatively flat at $28 billion, causing fewer grant proposals to be financed nationwide. But in an effort to at least maintain the level of support they received in previous years for their research efforts, local institutions have applied for more grants from NIH and have embarked on more collaborative research initiatives. They also have boosted their efforts to secure money from foundations and private industry sources, such as drug companies.

Case and its affiliates received new NIH grants totaling $131 million in the fiscal year that ended June 30, 2006. Already in the current fiscal year, which doesn't end until June 30, Case and its affiliates have received $160 million in new NIH grants, a 22% increase from last fiscal year's total, said Eric Cottington, associate vice president for research at Case.

Case's affiliates include University Hospitals Case Medical Center, the Clinic's Lerner College of Medicine at Case, MetroHealth and the veterans hospital.

Dr. Cottington notes that the number of grant proposals Case submitted also has risen nearly 11%, to 792 so far in fiscal 2007 from 715 in all of fiscal 2006.

``One of the ways to compensate for flat funding is to submit more proposals,'' Dr. Cottington said. ``If we submit more proposals, maybe we'll get more awards.''

Total NIH awards, including renewed grants, for Case and its affiliates will level off at about $250 million in the current fiscal year, Dr. Cottington said. Total NIH awards to those entities last year equaled $248 million, he said.

Phil Cola, vice president for research and technology at UH Case Medical Center, said his hospital has grown its NIH grant support by about 30% over the last five years.

``Despite increased competition and declining growth of the NIH budget, Case and (UH Case Medical Center) are still growing, compared to other academic medical centers, the amount of NIH dollars that come to Case,'' he said. ``We're holding our own and maybe a little bit more.''

The Clinic also seems to be commanding a larger part of the NIH budget. In the federal fiscal year that ended Sept. 30, 2005, the Clinic was awarded $83 million in NIH grants, up 13% from the $73 million it received the year before, Dr. DiCorleto said. In fiscal 2006, that figure rose 3% to $86 million, he said. He expects the Clinic to receive an additional 2% to 3% in NIH support this fiscal year.

Spirit of collaboration

While his researchers also have been applying for more grants, Dr. DiCorleto said they're also benefiting from new collaborations between Clinic departments and with other local research institutions. He said NIH director Dr. Elias Zerhouni has made it clear he favors collaborations, which help new treatments reach patients faster.

Mr. Cola said he believes collaborations with other institutions, including an affiliation agreement with Case, have helped UH tremendously in winning more NIH grants.

``The National Cancer Institute definitely looks more favorably on the Cleveland Clinic and UH partnering on cancer research,'' Mr. Cola said. He noted that when two institutions work together rather than compete, they can enroll more patients in clinical trials at a faster rate.

Grants from foundations and drugmakers also are up, Dr. Cottington said.

In 2006, Case received $11 million in research support from private companies, up 57% from $7 million in 2003. Foundations provided $14 million in research support for Case in 2006, an increase of 10% from the $12.7 million it received in 2003, Dr. Cottington said.

Mr. Cola said UH Case Medical Center has shifted much of its focus from NIH grants to private sources over the last five years to supplement NIH support and to keep top researchers in Cleveland. In turn, when the hospital is able to recruit top faculty who bring NIH grants with them, private support also usually increases, he said.

Since 2001, UH Case Medical Center has seen private research dollars more than double, to $27 million in 2006.

Mr. Cola said support from Ohio's Third Frontier technology development program also ``has helped alleviate the competitive pinch we've been feeling.''

Northeast Ohio institutions have received more than $300 million from the Third Frontier program since it began in 2004.

A firm grip locally

The research picture isn't as rosy across the country. According to a report released last month by eight universities - including Harvard, Yale and Johns Hopkins - some scientists have had to downsize their laboratories and halt projects.

``They report having to abandon some of their most productive collaborations and innovative work, as projects seen as risky are less likely to be funded,'' said the report, which was titled ``Within Our Grasp - or Slipping Away? Assuring a New Era of Scientific and Medical Progress.''

The report also noted that Asian and European countries are trying to lure young scientists to their countries with increased research dollars.

While those trends could be alarming, Clinic, Case and UH officials said they hadn't heard of those things happening in their institutions.

``We have not had people who have had to close down their programs because of a lack of significant funding,'' Dr. DiCorleto said. ``There are those that might be downsizing a bit, but very few investigators would give up on their major areas of research.''

And they might not have to do so. Dr. DiCorleto said he believes the NIH financing climate will improve because many of the research projects that were supported with multiyear grants will be expiring soon, so that money will be available for new projects.

``There (also) is a lot of congressional support for giving NIH a boost in the budget,'' he said.

LOAD-DATE: April 12, 2007




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